One night, at Al's chemical company Piguel O'Malley was working a late janitor shift. While working, Perfesser warned Piguel to stay away from the vat of Spider-Venom in the room before leaving. But fate has a strange way of unraveling...like a spider spinning its web.
Later Ductor Doom 2099 broke into the facility and accidentally bumped Piguel into the vat. Piguel was able to swim out, claiming that the Spider-Venom tasted like Dr. Pepper but without the fizz. Piguel soon learned that he had spider powers much like that of Peter Porker (his ancestor). He returned home and put on his super hero costume that he kept in his closet for emergencies. He then set out to find Ductor Doom 2099 as the all new hero... Spider-Ham 2099!