Martha Connors was married to Dr. Curt Connors (aka Lizard). They had one son together, Billy Connors.
She died at the hands of the Lizard, but the Jackal later brought Martha and her son back to life in order to convince Curt, having his intellect while trapped in the Lizard's body, to work for him. As the clone bodies started to degrade, Curt injected the Lizard serum into his wife and son in order to stabilize them.
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Created By: Stan Lee, Steve Ditko
First Appearance: Amazing Spider-Man #6 (November, 1963)