The nameless being later to be called Doomsday (by Booster Gold) was artificially created in the distant past on Krypton, long before the humanoid Kryptonian race had gained dominance over the planet.
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History
Nearly 250,000 years ago in Krypton’s past, a scientist named Bertron (not a native of Krypton himself) began genetic experiments with a team of fellow scientists he’d assembled, intending to create a perfect biological weapon. His test subject was an infant he’d brought from another world and exposed to the natural dangers and predators of Krypton. The infant did not survive long. Bertron had the infant’s remains examined and, after adjusting its genes slightly, created a clone. This process repeated every day for decades, allowing Bertron and his scientists to simulate and direct the effects of millions of years of evolution in a relatively short span of time.
This creature, “the Ultimate,” became a powerful biological weapon of destruction that could seemingly survive any environment, as well as any attack. Driven by an instinctive hatred for the native life on Krypton, he spent a few years hunting and killing local predators. Then, somehow understanding that Bertron was responsible for his dying repeatedly, the Ultimate returned to the lab that created him and killed everyone. Soon afterward a supply spaceship arrived, having been arranged by Bertron. The monster boarded it and used it to leave Krypton.
The Ultimate, who also earned the name “Armageddon Creature,” made his way to other planets, killing many innocents and warriors, including members of the Green Lantern Corps. He was finally defeated on the planet Calaton by an artificially created being called the Radiant. Had his body been destroyed there, Doomsday would have died. But the people of Calaton instead placed his body in a cage and buried it underground on the planet Earth.
Doomsday would eventually seek his way to Earth to do one important thing: bring the Man of Steel to his grave, sacrificing his life in the process.