The Annihilator was an enemy of Batgirl and Supergirl. Kenneth Anderson was a Gotham City scientist. Working as geologist for Vesper Research Laboratories, Anderson discovered a strange glowing rock. Guessing it came from space and contained an unknown kind of energy able to supply the whole country, Anderson made his finding public, but his discovery had little impact. Resentful and angry, Anderson set out to experiment with the stone, determined to unlock his power. Anderson managed to release a little fraction of its power, but his body was bathed by the strange energies released. Anderson evolved into some kind of large-headed mutant endowed with psychic powers. His changes also altered his emotions, driving him into a rage. Eager to punish those who he belittled him, Anderson went to blast Hinchcliff Research Laboratories down.