Maybelle "May" Parker is Peter Parker's aunt.
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History
May and Ben Parker took in their nephew Peter after the death of his parents and raised him. Ben immediately took to the role of the boy's father but May was at first reluctant. She still remembered her parents blaming her own birth for the destruction of their marriage, and she was afraid that Peter might signal the end of her own marriage. In time, however, she warmed up to Peter, who unexpectedly strengthened the couple's marriage. After Ben's death, life became a struggle with money problems and Peter did his best to help. Years after Ben Parker's unfortunate passing, May remarried to Jay Jameson (J. Jonah Jameson's father) and the two of them helped Peter run the Uncle Ben Foundation, a charity focused on providing help for the less fortunate and raise the quality of life wherever it could be possible.