Marinette, also known as Lost, was depowered on M-Day by Scarlet Witch. Like other mutants she lost her powers but her body did not change, leaving her deformed and in constant agony.
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Lost is a mutant with the ability to nullify gravity around herself. As a side effect of her power her body greatly changed from the norm. When she lost her power during Decimation she retained the physical changes. Being forced to live under normal gravity now, she was in a constant agony.
Years later, when the Krakoan nation was established, she came there for help in the hope to regain her power and finally alleviate the pain she constantly felt. Knowing that Crucible would require her to battle to the death, she turned to Nightcrawler for help, feeling that he would be merciful and would give her quick and easy death. Unfortunately, Kurt was too distracted by his own troubles, and refused to listen to her plea. Magneto became her opponent in Crucible instead and she was brutally beaten for a long time before death.
She was resurrected by the Five and happily regained her powers. However, her power also made everyone around her nauseous and start vomiting, so she quickly escaped from The Hatchery in tears and apologizing.