Gwen Poole originally lived in a universe not so unlike ours, a place where all superheroes and supervillains were fictional characters that manifested through comic books, movies, and other media. Together with her brother Teddy, she was accidentally sucked into the comic book world, and, believing her brother to be dead and uncertain of how to make her way back to the real world, she settled in to become Marvel's newest hero, the Unbelievable Gwenpool.
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History
Originally from the real universe, ordinary dropout Gwen Poole retreated from her daily struggles and failures by obsessing over the media that she loved, particularly the Marvel Universe. Gwen's difficulty to find a job after having been unable to graduate from high school, combined with the fact all of her friends moved away, led her to submerge in fiction in order to escape from her reality and fantasize about a better world, becoming lazy and apathetic, to the chagrin of her parents.
Through unrevealed means, Gwen and her brother Teddy ended up in the Prime Marvel Universe. However, both became separated on arrival, and believed the other hadn't survived the transition. Unwilling to being relegated as an "extra," Gwen went to Big Ronnie's Custom Battle Spandex and requested her own costume to stand out. The tailor Ronnie complied, but she also misread Gwen's form, and thought the young girl went by the alias of "Gwenpool."
Gwenpool's first misadventure involved stealing a virus from the Black Cat and selling it to Hydra for quick cash, believing that the Avengers would deal with any sort of consequence. When Gwenpool attempted to kill Howard the Duck, who had been coerced by the Black Cat into finding the thief, he made Gwen see the error in her nonchalant attitude, which originated from Gwen undervaluing the lives of the inhabitants of the Marvel Universe, whom she believed were nothing more than fictional characters. Gwen rectified her misdeed by infiltrating into a Hydra facility and getting rid of the virus with Howard's help.
In order to find a stable source of income, Gwen decided to become a mercenary, getting contract jobs from the tailor Ronnie. While trying to carry out the job of taking down a Teuthidan squadron stationed on Earth, Gwenpool murdered another mercenary that had completed said mission and took credit for his work. The employer of the hitman Gwen murdered turned out to be M.O.D.O.K., who tracked down Gwenpool to have her take the place of his deceased hitman in his Mercenary Organization Dedicated Only to Killing. In order to coerce her into joining his namesake organization, M.O.D.O.K. killed Cecil, a hacker Gwen befriended who had become her mission control. Gwenpool's teammates in M.O.D.O.K.'s elite were Batroc the Leaper, Mega Tony, and Terrible Eye.